Cholesterol Ester Transfer Protein Inhibitor Review
نویسندگان
چکیده
منابع مشابه
Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol.
BACKGROUND Decreased high-density lipoprotein (HDL) cholesterol levels constitute a major risk factor for coronary heart disease; however, there are no therapies that substantially raise HDL cholesterol levels. Inhibition of cholesteryl ester transfer protein (CETP) has been proposed as a strategy to raise HDL cholesterol levels. METHODS We conducted a single-blind, placebo-controlled study t...
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Cheng-ai Wu, Maki Tsujita, Kuniko Okumura-Noji, Shinichi Usui, Hajime Kakuuchi, Mitsuyo Deficient Mice − Cholesteryl Ester Transfer Protein Expressed in Lecithin Cholesterol Acyltransferase Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2002 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 A...
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Statins, inhibitors of the key enzyme in the biosynthesis of cholesterol (ie, 3-hydroxy-3-methylglutaryl [HMG]coenzyme A [CoA] reductase), are widely used as the prevailing strategy to combat atherosclerosis through reducing LDL cholesterol levels. Large-scale clinical trials have shown that statins markedly reduce coronary events.1,2 A meta-analysis of 22 studies enrolling nearly 70 000 indivi...
متن کاملSeparation of a plasma phospholipid transfer protein from cholesterol ester/phospholipid exchange protein.
The d > 1.21 g/ml fraction of human plasma stimulates mass transfer of phosphatidylcholine (PC) from egg PC vesicles into plasma high density lipoproteins (HDL) and also exchange of PC and cholesterol esters (CE) between HDL and low density lipoproteins (LDL). By measuring the facilitated transfer of PC from egg PC vesicles into HDL, and the facilitated exchange of cholesterol esters between HD...
متن کاملPlasma cholesteryl ester transfer protein.
The plasma lipoproteins are continuously remodeled during their transit through the plasma compartment, owing to the action of lipid metabolizing enzymes and lipid transfer processes. These activities have a major effect on the composition, size, and concentration of the lipoproteins. Lipid transfer processes involving neutral lipids and phospholipids are mediated by specialized plasma proteins...
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ژورنال
عنوان ژورنال: Hospital Pharmacy
سال: 2017
ISSN: 0018-5787,1945-1253
DOI: 10.1177/0018578717729669